June 03, 2022

DENS Grows with Biopharmaceutical Company as It Harnesses a Revolution in Human Health

Founded in the early 2000s, this biopharmaceutical company develops RNAi therapeutics – an innovative new class of medicines that work by disabling the production of genes that cause specific diseases.

In less than 20 years, this client has grown from a small start-up to a top-tier global biopharmaceutical company with multiple approved products and several programs in clinical development.

The Challenge

As interest in RNAi grew during the early 2000s, the biopharmaceutical client experienced a period of sudden and rapid growth that necessitated a facilities services upgrade. Not only did laboratory equipment require extensive repair, but cleaning and sanitation demanded a renewed focus.

Meanwhile, the client struggled to obtain and manage the lab supplies and other inventory needed to broaden its research and development. One of the chemicals that it needed to secure was buffer – the substance that helps maintain a relatively constant pH in a solution – which became increasingly difficult to source once the COVID-19 pandemic began.

The company turned to DENS to provide a combination of facilities management and lab support services.

The Solution

Partnering with the client, DENS reset the non-working centrifuges and repaired other nonfunctioning equipment so that the client could resume working at a routine pace. The team also began self-performing preventative and predictive maintenance.

With the lab facilities stabilized, the DENS team set out to improve day-to-day lab operations, first by enforcing new operating procedures to ensure the client’s glassware and other fixtures remained in good working condition.

Additionally, DENS began managing the client’s inventory of chemicals and gases – a crucial part of lab preparation.

DENS also introduced experts capable of producing buffer in-house for the client. Quickly, the buffer prep team fortified its supply and began supplying buffer across the client business.

The Outcome

After three years of partnership, DENS has helped to refine the client’s facilities services processes and procedures and increased communication and transparency among all invested parties. Thusly, the company is positioned for the growth and success that its mission so deserves.

As this growth continues, so does DENS’ role within the organization. Since the partnership began, the DENS team has more than doubled. And, with DENS’ help, there are plans to triple the size of the buffer team by the end of 2022.

Today, the client provides buffer to 100 scientists in total, with hopes of expanding the program and marketing the product to a wider base. By taking control of this critical component, the client can guarantee the avoidance of future disruptions caused by supply shortages.

The client is now an industry leader with a robust pipeline of therapeutics – a testament to the power of its partnership with DENS. As a result, the company can remain focused on building its research and development engine and harnessing a revolution in biology for human health.